A Single Base-Pair Change in 2009 H1N1 Hemagglutinin Increases Human Receptor Affinity and Leads to Efficient Airborne Viral Transmission in Ferrets
The 2009 H1N1 influenza A virus continues to circulate among the human population as the predominant H1N1 subtype. Epidemiological studies and airborne transmission studies using the ferret model have shown that the transmission efficiency of 2009 H1N1 viruses is lower than that of previous seasonal...
Main Authors: | Jayaraman, Akila, Pappas, Claudia, Raman, Rahul, Belser, Jessica A., Viswanathan, Karthik, Tumpey, Terrence M., Sasisekharan, Ram, Shriver, Zachary H. |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2011
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Online Access: | http://hdl.handle.net/1721.1/65575 https://orcid.org/0000-0002-1288-9965 https://orcid.org/0000-0001-9344-0205 https://orcid.org/0000-0002-2085-7840 |
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