Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis

Abstract Background Among its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating retinoic acid receptor (RAR)-mediated transcription. RAR is thought to bind the genome constitutively, and only induce transcription in...

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Bibliographic Details
Main Authors: Mahony, Shaun, Mazzoni, Esteban O., McCuine, Scott, Young, Richard A., Wichterle, Hynek, Gifford, David K.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: BioMed Central Ltd. 2011
Online Access:http://hdl.handle.net/1721.1/65633
https://orcid.org/0000-0003-1709-4034