Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis
Abstract Background Among its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating retinoic acid receptor (RAR)-mediated transcription. RAR is thought to bind the genome constitutively, and only induce transcription in...
Main Authors: | Mahony, Shaun, Mazzoni, Esteban O., McCuine, Scott, Young, Richard A., Wichterle, Hynek, Gifford, David K. |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | en_US |
Published: |
BioMed Central Ltd.
2011
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Online Access: | http://hdl.handle.net/1721.1/65633 https://orcid.org/0000-0003-1709-4034 |
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