Hemodynamic Environments from Opposing Sides of Human Aortic Valve Leaflets Evoke Distinct Endothelial Phenotypes In Vitro

Hemodynamic Environments from Opposing Sides of Human Aortic Valve Leaflets Evoke Distinct Endothelial Phenotypes In Vitro

The regulation of valvular endothelial phenotypes by the hemodynamic environments of the human aortic valve is poorly understood. The nodular lesions of calcific aortic stenosis (CAS) develop predominantly beneath the aortic surface of the valve leaflets in the valvular fibrosa layer. However, the m...

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Bibliographic Details
Main Authors: Weinberg, Eli J., Mack, Peter J., Shoen, Frederick J., Garcia-Cardena, Guillermo, Kaazempur Mofrad, Mohammad R.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Springer Science + Business Media B.V. 2011
Online Access:http://hdl.handle.net/1721.1/65840

Internet

http://hdl.handle.net/1721.1/65840

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