Quantifying the biophysical characteristics of Plasmodium-falciparum- parasitized red blood cells in microcirculation

The pathogenicity of Plasmodium falciparum (Pf) malaria results from the stiffening of red blood cells (RBCs) and its ability to adhere to endothelial cells (cytoadherence). The dynamics of Pf-parasitized RBCs is studied by three-dimensional mesoscopic simulations of flow in cylindrical capillaries...

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Bibliographic Details
Main Authors: Fedosov, Dmitry A., Caswell, Bruce, Suresh, Subra, Karniadakis, George E.
Other Authors: Massachusetts Institute of Technology. Department of Materials Science and Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2011
Online Access:http://hdl.handle.net/1721.1/65952
https://orcid.org/0000-0002-6223-6831