Microfluidic Perfusion for Regulating Diffusible Signaling in Stem Cells
Background Autocrine & paracrine signaling are widespread both in vivo and in vitro, and are particularly important in embryonic stem cell (ESC) pluripotency and lineage commitment. Although autocrine signaling via fibroblast growth factor-4 (FGF4) is known to be required in mouse ESC (mESC)...
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Format: | Article |
Language: | en_US |
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Public Library of Science
2011
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Online Access: | http://hdl.handle.net/1721.1/66169 https://orcid.org/0000-0001-8898-2296 |