Microfluidic Perfusion for Regulating Diffusible Signaling in Stem Cells

Background Autocrine & paracrine signaling are widespread both in vivo and in vitro, and are particularly important in embryonic stem cell (ESC) pluripotency and lineage commitment. Although autocrine signaling via fibroblast growth factor-4 (FGF4) is known to be required in mouse ESC (mESC)...

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Bibliographic Details
Main Authors: Blagovic, Katarina, Kim, Lily Y., Voldman, Joel
Other Authors: Whitaker College of Health Sciences and Technology
Format: Article
Language:en_US
Published: Public Library of Science 2011
Online Access:http://hdl.handle.net/1721.1/66169
https://orcid.org/0000-0001-8898-2296