Multicoil2: predicting coiled coils and their oligomerization States from sequence in the twilight zone

The alpha-helical coiled coil can adopt a variety of topologies, among the most common of which are parallel and antiparallel dimers and trimers. We present Multicoil2, an algorithm that predicts both the location and oligomerization state (two versus three helices) of coiled coils in protein sequen...

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Bibliographic Details
Main Authors: Gutwin, Karl, Keating, Amy E., Trigg, Jason, Berger Leighton, Bonnie
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Public Library of Science 2011
Online Access:http://hdl.handle.net/1721.1/66190
https://orcid.org/0000-0003-4074-8980
https://orcid.org/0000-0002-2724-7228