Multicoil2: predicting coiled coils and their oligomerization States from sequence in the twilight zone
The alpha-helical coiled coil can adopt a variety of topologies, among the most common of which are parallel and antiparallel dimers and trimers. We present Multicoil2, an algorithm that predicts both the location and oligomerization state (two versus three helices) of coiled coils in protein sequen...
Main Authors: | Gutwin, Karl, Keating, Amy E., Trigg, Jason, Berger Leighton, Bonnie |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2011
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Online Access: | http://hdl.handle.net/1721.1/66190 https://orcid.org/0000-0003-4074-8980 https://orcid.org/0000-0002-2724-7228 |
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