Suppression of Lung Adenocarcinoma Progression by Nkx2-1

Despite the high prevalence and poor outcome of patients with metastatic lung cancer the mechanisms of tumour progression and metastasis remain largely uncharacterized. Here we modelled human lung adenocarcinoma, which frequently harbours activating point mutations in KRAS and inactivation of th...

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Bibliographic Details
Main Authors: Winslow, Monte Meier, Dayton, Talya Lucia, Kim-Kiselak, Caroline, Snyder, Eric, Feldser, David M., DuPage, Michel J., Whittaker, Charles A., Hoersch, Sebastian, Yoon, Stephanie M., Crowley, Denise G., Verhaak, Roel G., Hubbard, Diana D., Chiang, Derek Y., Myerson, Matthew, Bronson, Roderick T., Jacks, Tyler E
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2011
Online Access:http://hdl.handle.net/1721.1/66248
https://orcid.org/0000-0001-5785-8911
https://orcid.org/0000-0002-7994-7963