Caenorhabditis elegans aristaless/Arx gene alr-1 restricts variable gene expression

Variable expressivity of mutant phenotypes in genetically identical individuals is a phenomenon widely reported but poorly understood. For example, mutations in the gene encoding the transcription factor ALR-1 in Caenorhabditis elegans result in variable touch receptor neuron (TRN) function. Using s...

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Bibliographic Details
Main Authors: Topalidou, Irini, van Oudenaarden, Alexander, Chalfie, Martin
Other Authors: Massachusetts Institute of Technology. Department of Physics
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2011
Online Access:http://hdl.handle.net/1721.1/66269