Human CD34+ CD133+ Hematopoietic Stem Cells Cultured with Growth Factors Including Angptl5 Efficiently Engraft Adult NOD-SCID Il2rγ−/− (NSG) Mice

Human CD34+ CD133+ Hematopoietic Stem Cells Cultured with Growth Factors Including Angptl5 Efficiently Engraft Adult NOD-SCID Il2rγ−/− (NSG) Mice

Increasing demand for human hematopoietic stem cells (HSCs) in clinical and research applications necessitates expansion of HSCs in vitro. Before these cells can be used they must be carefully evaluated to assess their stem cell activity. Here, we expanded cord blood CD34+ CD133+ cells in a defined...

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Bibliographic Details
Main Authors: Drake, Adam, Khoury, Maroun, Leskov, Ilya B., Iliopoulou, Bettina P., Fragoso, Maria F., Lodish, Harvey F., Chen, Jianzhu
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Public Library of Science 2011
Online Access:http://hdl.handle.net/1721.1/66282
https://orcid.org/0000-0002-7029-7415
https://orcid.org/0000-0002-5687-6154

Internet

http://hdl.handle.net/1721.1/66282
https://orcid.org/0000-0002-7029-7415
https://orcid.org/0000-0002-5687-6154

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