DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts

DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts

Base excision repair (BER) is a DNA repair pathway designed to correct small base lesions in genomic DNA. While DNA polymerase beta (pol β) is known to be the main polymerase in the BER pathway, various studies have implicated other DNA polymerases in back-up roles. One such polymerase, DNA polymera...

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Bibliographic Details
Main Authors: Braithwaite, Elena K., Kedar, Padmini S., Stumpo, Deborah J., Bertocci, Barbara, Freedman, Jonathan H., Samson, Leona D., Wilson, Samuel H.
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: Public Library of Science 2011
Online Access:http://hdl.handle.net/1721.1/66510
https://orcid.org/0000-0002-7112-1454

Internet

http://hdl.handle.net/1721.1/66510
https://orcid.org/0000-0002-7112-1454

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