Uncoupling cancer mutations reveals critical timing of p53 loss in sarcomagenesis
It is well accepted that cancer develops following the sequential accumulation of multiple alterations, but how the temporal order of events affects tumor initiation and/or progression remains largely unknown. Here, we describe a mouse model that allows for temporally distinct cancer mutations. By i...
Váldodahkkit: | , , |
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Eará dahkkit: | |
Materiálatiipa: | Artihkal |
Giella: | en_US |
Almmustuhtton: |
American Association for Cancer Research
2011
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Liŋkkat: | http://hdl.handle.net/1721.1/66517 https://orcid.org/0000-0001-5785-8911 |