An essential role for XBP-1 in host protection against immune activation in C. elegans

The detection and compensatory response to the accumulation of unfolded proteins in the endoplasmic reticulum (ER), termed the unfolded protein response (UPR), represents a conserved cellular homeostatic mechanism with important roles in normal development and in the pathogenesis of disease1. The IR...

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Bibliographic Details
Main Authors: Richardson, Claire Elissa, Kooistra, Tristan G., Kim, Dennis H.
Other Authors: Whitaker College of Health Sciences and Technology
Format: Article
Language:en_US
Published: Nature Publishing Group 2011
Online Access:http://hdl.handle.net/1721.1/66544
https://orcid.org/0000-0002-4109-5152