Potent inhibition of cartilage biosynthesis by coincubation with joint capsule through an IL-1-independent pathway

The reason for the increased risk for development of osteoarthritis (OA) after acute joint trauma is not well understood, but the mechanically injured cartilage may be more susceptible to degradative mediators secreted by other tissues in the joint. To establish a model for such interactions, we coi...

Full description

Bibliographic Details
Main Authors: Grodzinsky, Alan J., Patwari, P., Lin, S. N., Kurz, Bodo, Cole, Ada A., Kumar, S.
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering
Format: Article
Language:en_US
Published: John Wiley & Sons, Inc. 2011
Online Access:http://hdl.handle.net/1721.1/66583
https://orcid.org/0000-0002-4942-3456