Adult equine bone-marrow stromal cells produce a cartilage-like ECM superior to animal-matched adult chondrocytes

Our objective was to evaluate the age-dependent mechanical phenotype of bone marrow stromal cell- (BMSC-) and chondrocyte-produced cartilage-like neo-tissue and to elucidate the matrix-associated mechanisms which generate this phenotype. Cells from both immature (2–4 month-old foals) and skeletally-...

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Bibliographic Details
Main Authors: Kisiday, John D., Frisbie, David D., Plaas, A. H. K., Kopesky, Paul Wayne, Leeb, Steven B., Vanderploeg, Eric J., Ortiz, Christine, Grodzinsky, Alan J.
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering
Format: Article
Language:en_US
Published: Elsevier Ltd. 2011
Online Access:http://hdl.handle.net/1721.1/66584
https://orcid.org/0000-0003-3511-5679
https://orcid.org/0000-0002-3856-6005
https://orcid.org/0000-0003-0026-6215
https://orcid.org/0000-0002-4942-3456