Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine

Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine

The development of molecular probes that allow in vivo imaging of neural signaling processes with high temporal and spatial resolution remains challenging. Here we applied directed evolution techniques to create magnetic resonance imaging (MRI) contrast agents sensitive to the neurotransmitter dopam...

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Bibliographic Details
Main Authors: Shapiro, Mikhail G., Westmeyer, Gil Gregor, Szablowski, Jerzy O., Küster, Benedict, Shah, Ameer, Langer, Robert, Jasanoff, Alan Pradip, Romero, Philip A., Arnold, Frances H., Otey, Christopher R.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Company 2011
Online Access:http://hdl.handle.net/1721.1/66682
https://orcid.org/0000-0002-2834-6359
https://orcid.org/0000-0003-3975-3221
https://orcid.org/0000-0003-4255-0492

Internet

http://hdl.handle.net/1721.1/66682
https://orcid.org/0000-0002-2834-6359
https://orcid.org/0000-0003-3975-3221
https://orcid.org/0000-0003-4255-0492

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