MRI sensing based on the displacement of paramagnetic ions from chelated complexes
We introduce a mechanism for ion sensing by MRI in which analytes compete with paramagnetic ions for binding to polydentate chelating agents. Displacement of the paramagnetic ions results in alteration of solvent interaction parameters and consequent changes in relaxivity and MRI contrast. The MRI c...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
American Chemical Society
2011
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| Online Access: | http://hdl.handle.net/1721.1/66683 https://orcid.org/0000-0002-2834-6359 https://orcid.org/0000-0002-2693-4982 |