A mathematical model for targeting chemicals to tissues by exploiting complex degradation

Background In many biological and therapeutic contexts, it is highly desirable to target a chemical specifically to a particular tissue where it exerts its biological effect. In this paper, we present a simple, generic, mathematical model that elucidates a general method for targeting a chemical to...

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Bibliographic Details
Main Authors: Gardiner, Bruce S., Zhang, Lihai, Smith, David W., Pivonka, Peter, Grodzinsky, Alan J.
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering
Format: Article
Language:English
Published: BioMed Central Ltd 2011
Online Access:http://hdl.handle.net/1721.1/66687
https://orcid.org/0000-0002-4942-3456