DNA repair modulates the vulnerability of the developing brain to alkylating agents

DNA repair modulates the vulnerability of the developing brain to alkylating agents

Neurons of the developing brain are especially vulnerable to environmental agents that damage DNA (i.e., genotoxicants), but the mechanism is poorly understood. The focus of the present study is to demonstrate that DNA damage plays a key role in disrupting neurodevelopment. To examine this hypothesi...

Full description

Bibliographic Details
Main Authors: Samson, Leona D., Kisby, Glen E., Olivas, A., Park, T., Churchwell, Mona, Doerge, Daniel R., Gerson, S. L., Turker, M. S.
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: Elsevier Pub. Co. 2011
Online Access:http://hdl.handle.net/1721.1/66890
https://orcid.org/0000-0002-7112-1454

Internet

http://hdl.handle.net/1721.1/66890
https://orcid.org/0000-0002-7112-1454

Similar Items