Compounds from an Unbiased Chemical Screen Reverse Both Er-to-Golgi Trafficking Defects and Mitochondrial Dysfunction in Parkinson's Disease Models

Compounds from an Unbiased Chemical Screen Reverse Both Er-to-Golgi Trafficking Defects and Mitochondrial Dysfunction in Parkinson's Disease Models

α-Synuclein (α-syn) is a small lipid-binding protein involved in vesicle trafficking whose function is poorly characterized. It is of great interest to human biology and medicine because α-syn dysfunction is associated with several neurodegenerative disorders, including Parkinson’s disease (PD). We...

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Bibliographic Details
Main Authors: Su, Linhui Julie, Auluck, Pavan K., Outeiro, Tiago Fleming, Yeger-Lotem, Esti, Kritzer, Joshua A., Tardiff, Daniel F., Bell, George W., Fraenkel, Ernest, Lindquist, Susan, Strathearn, Katherine E., Liu, Fang, Cao, Songsong, Hamamichi, Shusei, Hill, Kathryn J., Caldwell, Kim A., Cooper, Antony A., Caldwell, Guy A., McCaffery, J. Michael, Rochet, Jean-Christophe
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Company of Biologists Limited 2011
Online Access:http://hdl.handle.net/1721.1/66913
https://orcid.org/0000-0003-1307-882X
https://orcid.org/0000-0001-9249-8181

Internet

http://hdl.handle.net/1721.1/66913
https://orcid.org/0000-0003-1307-882X
https://orcid.org/0000-0001-9249-8181

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