Combined logical and data-driven models for linking signalling pathways to cellular response
Background Signalling pathways are the cornerstone on understanding cell function and predicting cell behavior. Recently, logical models of canonical pathways have been optimised with high-throughput phosphoproteomic data to construct cell-type specific pathways. However, less is known on how sig...
Main Authors: | Melas, Ioannis N., Mitsos, Alexander, Messinis, Dimitris E., Weiss, Thomas S., Alexopoulos, Leonidas G. |
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Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering |
Format: | Article |
Language: | en_US |
Published: |
BioMed Central Ltd.
2011
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Online Access: | http://hdl.handle.net/1721.1/66963 |
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