An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing Glioblastoma Cells

An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing Glioblastoma Cells

Glioblastoma (GBM, WHO grade IV) is an aggressively proliferative and invasive brain tumor that carries a poor clinical prognosis with a median survival of 9 to 12 months. In a prior phosphoproteomic study performed in the U87MG glioblastoma cell line, we identified tyrosine phosphorylation events t...

Full description

Bibliographic Details
Main Authors: Naegle, Kristen Marie, Huang, Paul H., White, Forest M., Joughin, Brian Alan, Yaffe, Michael B, Lauffenburger, Douglas A
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2011
Online Access:http://hdl.handle.net/1721.1/67037
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0002-9547-3251

Internet

http://hdl.handle.net/1721.1/67037
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0002-9547-3251

Similar Items