A General Method for Quantifying Sequence Effects on Nucleobase Oxidation in DNA

Oxidative damage to DNA has long been associated with aging and disease, with guanine serving as the primary target for oxidation owing to its low ionization potential. Emerging evidence points to a critical role for sequence context as a determinant of the guanine ionization potential and the asso...

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Bibliográfalaš dieđut
Váldodahkkit: Margolin, Yelena, Dedon, Peter C.
Eará dahkkit: Massachusetts Institute of Technology. Department of Biological Engineering
Materiálatiipa: Artihkal
Giella:en_US
Almmustuhtton: Springer Science+Business Media 2011
Liŋkkat:http://hdl.handle.net/1721.1/67254
https://orcid.org/0000-0003-0011-3067