Conditional Deletion of IkappaB-Kinase-beta Accelerates Helicobacter-Dependent Gastric Apoptosis, Proliferation, and Preneoplasia

Conditional Deletion of IkappaB-Kinase-beta Accelerates Helicobacter-Dependent Gastric Apoptosis, Proliferation, and Preneoplasia

Background & Aims: The nuclear factor κB (NF-κB)/IκB-kinase-β (IKKβ) pathway has been shown to represent a key link between inflammation and cancer, inducing pro-inflammatory cytokines in myeloid cells and anti-apoptotic pathways in epithelial cells. However, the role of NF-κB pathway in gast...

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Bibliographic Details
Main Authors: Shibata, Wataru, Takaishi, Shigeo, Muthupalani, Sureshkumar, Pritchard, D. Mark, Whary, Mark T., Rogers, Arlin B., Fox, James G., Betz, Kelly S., Kaestner, Klaus H., Karin, Michael, Wang, Timothy C.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier B.V. 2011
Online Access:http://hdl.handle.net/1721.1/67281
https://orcid.org/0000-0001-9307-6116

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http://hdl.handle.net/1721.1/67281
https://orcid.org/0000-0001-9307-6116

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