Irradiated Esophageal Cells are Protected from Radiation-Induced Recombination by MnSOD Gene Therapy

Irradiated Esophageal Cells are Protected from Radiation-Induced Recombination by MnSOD Gene Therapy

Radiation-induced DNA damage is a precursor to mutagenesis and cytotoxicity. During radiotherapy, exposure of healthy tissues can lead to severe side effects. We explored the potential of mitochondrial SOD (MnSOD) gene therapy to protect esophageal, pancreatic and bone marrow cells from radiation-in...

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Bibliographic Details
Main Authors: Niu, Yunyun, Wang, Hong, Wiktor-Brown, Dominika, Rugo, Rebecca, Shen, Hongmei, Huq, Saiful, Engelward, Bevin P., Epperley, Michael, Greenberger, Joel S.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Radiation Research Society 2011
Online Access:http://hdl.handle.net/1721.1/67297

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http://hdl.handle.net/1721.1/67297

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