Structure of the EGF receptor transactivation circuit integrates with cell context

Structure of the EGF receptor transactivation circuit integrates with cell context

Transactivation of the epidermal growth factor receptor (EGFR) is thought to be a process by which a variety of cellular inputs can be integrated into a single signaling pathway through either stimulated proteolysis (shedding) of membrane-anchored EGFR ligands or by modification of the activity of t...

Full description

Bibliographic Details
Main Authors: Joslin, Elizabeth J., Shankaran, Harish, Opresko, Lee K., Bollinger, Nikki, Lauffenburger, Douglas A., Wiley, H. Steven
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2012
Online Access:http://hdl.handle.net/1721.1/68646

Internet

http://hdl.handle.net/1721.1/68646

Similar Items