Opportunities in metabolic engineering to facilitate scalable alkaloid production

Numerous drugs and drug precursors in the current pharmacopoeia originate from plant sources. The limited yield of some bioactive compounds in plant tissues, however, presents a significant challenge for large-scale drug development. Metabolic engineering has facilitated the development of plant cel...

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Bibliographic Details
Main Authors: Leonard, Effendi, Runguphan, Weerawat, O'Connor, Sarah Ellen, Prather, Kristala L. Jones
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2012
Online Access:http://hdl.handle.net/1721.1/68707
https://orcid.org/0000-0003-0437-3157