Interstitial flow influences direction of tumor cell migration through competing mechanisms

Interstitial flow is the convective transport of fluid through tissue extracellular matrix. This creeping fluid flow has been shown to affect the morphology and migration of cells such as fibroblasts, cancer cells, endothelial cells, and mesenchymal stem cells. A microfluidic cell culture system was...

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Bibliographic Details
Main Authors: Charest, Joseph L., Polacheck, William Joseph, Kamm, Roger Dale
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Proceedings of the National Academy of Sciences (PNAS) 2012
Online Access:http://hdl.handle.net/1721.1/69002
https://orcid.org/0000-0003-2728-0746
https://orcid.org/0000-0002-7232-304X