Interstitial flow influences direction of tumor cell migration through competing mechanisms
Interstitial flow is the convective transport of fluid through tissue extracellular matrix. This creeping fluid flow has been shown to affect the morphology and migration of cells such as fibroblasts, cancer cells, endothelial cells, and mesenchymal stem cells. A microfluidic cell culture system was...
Main Authors: | Charest, Joseph L., Polacheck, William Joseph, Kamm, Roger Dale |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Proceedings of the National Academy of Sciences (PNAS)
2012
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Online Access: | http://hdl.handle.net/1721.1/69002 https://orcid.org/0000-0003-2728-0746 https://orcid.org/0000-0002-7232-304X |
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