Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity

Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity

The HDL receptor, scavenger receptor, class B, type I (SR-BI), is a homooligomeric cell surface glycoprotein that controls HDL structure and metabolism by mediating the cellular selective uptake of lipids, mainly cholesteryl esters, from HDL. The mechanism underlying SR-BI-mediated lipid transfer, w...

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Bibliographic Details
Main Authors: Saenz-Vash, Veronica, Romer, Katherine A., Xu, Shangzhe, Yesilaltay, Ayce, Krieger, Monty, Yu, Miao, Nieland, Thomas J, Penman, Marsha L, Carr, Steven A
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Proceedings of the National Academy of Sciences (PNAS) 2012
Online Access:http://hdl.handle.net/1721.1/69003
https://orcid.org/0000-0003-4541-5181
https://orcid.org/0000-0003-2673-1672
https://orcid.org/0000-0002-7203-4299
https://orcid.org/0000-0002-5503-182X
https://orcid.org/0000-0001-9905-5316

Internet

http://hdl.handle.net/1721.1/69003
https://orcid.org/0000-0003-4541-5181
https://orcid.org/0000-0003-2673-1672
https://orcid.org/0000-0002-7203-4299
https://orcid.org/0000-0002-5503-182X
https://orcid.org/0000-0001-9905-5316

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