Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner

Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner

Whereas the roles of proangiogenic factors in carcinogenesis are well established, those of endogenous angiogenesis inhibitors (EAIs) remain to be fully elaborated. We investigated the roles of three EAIs during de novo tumorigenesis to further test the angiogenic balance hypothesis, which suggests...

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Bibliographic Details
Main Authors: Xie, Liang, Duncan, Michael B., Pahler, Jessica, Sugimoto, Hikaru, Martino, Margot, Lively, Julie, Mundel, Thomas, Soubasakos, Mary, Takeda, Takaaki, Inoue, Masahiro, Lawler, Jack, Hanahan, Douglas, Rubin, Kristofer, Kalluri, Raghu, Hynes, Richard O
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Proceedings of the National Academy of Sciences (PNAS) 2012
Online Access:http://hdl.handle.net/1721.1/69020
https://orcid.org/0000-0001-7603-8396

Internet

http://hdl.handle.net/1721.1/69020
https://orcid.org/0000-0001-7603-8396

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