A Novel Role of the WNT-Dishevelled-GSK3β Signaling Cascade in the Mouse Nucleus Accumbens in a Social Defeat Model of Depression

A Novel Role of the WNT-Dishevelled-GSK3β Signaling Cascade in the Mouse Nucleus Accumbens in a Social Defeat Model of Depression

Based on earlier gene expression and chromatin array data, we identified the protein, dishevelled (DVL)-2, as being regulated in the nucleus accumbens (NAc), a key brain reward region, in the mouse social defeat model of depression. Here, we validate these findings by showing that DVL2 mRNA and prot...

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Bibliographic Details
Main Authors: Wilkinson, Matthew B., Dias, Caroline, Magida, Jane, Mazei-Robison, Michelle S., Lobo, Mary Kay, Kennedy, Pamela J., Dietz, David M., Covington III, Herbert E., Russo, Scott, Ghose, Subroto, Tamminga, Carol, Nestler, Eric J., Neve, Rachael L.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Society for Neuroscience 2012
Online Access:http://hdl.handle.net/1721.1/69056
https://orcid.org/0000-0002-3854-5968

Internet

http://hdl.handle.net/1721.1/69056
https://orcid.org/0000-0002-3854-5968

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