Cdk5 Is Required for Memory Function and Hippocampal Plasticity via the cAMP Signaling Pathway
Memory formation is modulated by pre- and post-synaptic signaling events in neurons. The neuronal protein kinase Cyclin-Dependent Kinase 5 (Cdk5) phosphorylates a variety of synaptic substrates and is implicated in memory formation. It has also been shown to play a role in homeostatic regulation of...
Main Authors: | Zhu, J. Julius, Clauser, Karl R., Guan, Ji-Song, Gao, Jun, Xie, Zhigang, Zhou, Ying, Durak, Omer, Tsai, Li-Huei, Zhang, Lei, Ph. D Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, fl. 2014., Carr, Steven A, Su, S., Joseph, Nadine F. |
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Other Authors: | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2012
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Online Access: | http://hdl.handle.net/1721.1/69083 https://orcid.org/0000-0002-7203-4299 https://orcid.org/0000-0003-1262-0592 https://orcid.org/0000-0001-8426-6188 |
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