Nonlinear optical microscopy: use of second harmonic generation and two-photon microscopy for automated quantitative liver fibrosis studies

Nonlinear optical microscopy: use of second harmonic generation and two-photon microscopy for automated quantitative liver fibrosis studies

Liver fibrosis is associated with an abnormal increase in an extracellular matrix in chronic liver diseases. Quantitative characterization of fibrillar collagen in intact tissue is essential for both fibrosis studies and clinical applications. Commonly used methods, histological staining followed by...

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Bibliographic Details
Main Authors: Sun, Wanxin, Chang, Shi, Tai, Dean C. S., Tan, Nancy, Xiao, Guangfa, Tang, Huihuan, Yu, Hanry
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: SPIE - International Society for Optical Engineering 2012
Online Access:http://hdl.handle.net/1721.1/69125
https://orcid.org/0000-0002-0339-3685

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http://hdl.handle.net/1721.1/69125
https://orcid.org/0000-0002-0339-3685

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