A high-throughput microfluidic device to study neurite response to growth factor gradients

Studying neurite guidance by diffusible or substrate bound gradients is challenging with current techniques. In this study, we present the design, fabrication and utility of a microfluidic device to study neurite guidance under chemogradients. Experimental and computational studies demonstrated the...

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Bibliographic Details
Main Authors: Kothapalli, Chandrasekhar R., de Valence, Sarra, Chung, Seok, Zervantonakis, Ioannis, Gertler, Frank, Kamm, Roger Dale, Van Veen, John
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2012
Online Access:http://hdl.handle.net/1721.1/69153
https://orcid.org/0000-0003-3214-4554
https://orcid.org/0000-0002-7232-304X