Functional Heterogeneity of Breast Fibroblasts Is Defined by a Prostaglandin Secretory Phenotype that Promotes Expansion of Cancer-Stem Like Cells

Functional Heterogeneity of Breast Fibroblasts Is Defined by a Prostaglandin Secretory Phenotype that Promotes Expansion of Cancer-Stem Like Cells

Fibroblasts are important in orchestrating various functions necessary for maintaining normal tissue homeostasis as well as promoting malignant tumor growth. Significant evidence indicates that fibroblasts are functionally heterogeneous with respect to their ability to promote tumor growth, but mark...

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Bibliographic Details
Main Authors: Gupta, Piyush, Rudnick, Jenny A., Arendt, Lisa M., Klebba, Ina, Hinds, John W., Iyer, Vandana, Naber, Stephen P., Kuperwasser, Charlotte
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Public Library of Science 2012
Online Access:http://hdl.handle.net/1721.1/69165
https://orcid.org/0000-0002-9703-1780

Internet

http://hdl.handle.net/1721.1/69165
https://orcid.org/0000-0002-9703-1780

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