A large scale survey reveals that chromosomal copy-number alterations significantly affect gene modules involved in cancer initiation and progression

Background Recent observations point towards the existence of a large number of neighborhoods composed of functionally-related gene modules that lie together in the genome. This local component in the distribution of the functionality across chromosomes is probably affecting the own chromosomal a...

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Bibliographic Details
Main Authors: Alloza, Eva, Cigudosa, Juan C., Dopazo, Joaquín, Al-Shahrour, Fatima
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:en_US
Published: Springer (Biomed Central Ltd.) 2012
Online Access:http://hdl.handle.net/1721.1/69551