Amide I’-II’ 2D IR spectroscopy provides enhanced protein secondary structural sensitivity

Amide I’-II’ 2D IR spectroscopy provides enhanced protein secondary structural sensitivity

We demonstrate how multimode 2D IR spectroscopy of the protein amide I′ and II′ vibrations can be used to distinguish protein secondary structure. Polarization-dependent amide I′−II′ 2D IR experiments on poly-l-lysine in the β-sheet, α-helix, and random coil conformations show that a combination of...

Full description

Bibliographic Details
Main Authors: DeFlores, Lauren P., Ganim, Ziad, Nicodemus, Rebecca A., Tokmakoff, Andrei
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society 2012
Online Access:http://hdl.handle.net/1721.1/69554

Internet

http://hdl.handle.net/1721.1/69554

Similar Items