Amide I’-II’ 2D IR spectroscopy provides enhanced protein secondary structural sensitivity

We demonstrate how multimode 2D IR spectroscopy of the protein amide I′ and II′ vibrations can be used to distinguish protein secondary structure. Polarization-dependent amide I′−II′ 2D IR experiments on poly-l-lysine in the β-sheet, α-helix, and random coil conformations show that a combination of...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: DeFlores, Lauren P., Ganim, Ziad, Nicodemus, Rebecca A., Tokmakoff, Andrei
Muut tekijät: Massachusetts Institute of Technology. Department of Chemistry
Aineistotyyppi: Artikkeli
Kieli:en_US
Julkaistu: American Chemical Society 2012
Linkit:http://hdl.handle.net/1721.1/69554