Synthesis of 7-aminocoumarin via Buchwald-Hartwig cross coupling for specific protein labeling in living cells

To enable minimally invasive studies of proteins in their native context, it is desirable to tag proteins with small, bright reporter groups. Recently, our lab described PRIME technology (for PRobe Incorporation Mediated by Enzymes) for such tagging[1-3]. An engineered variant of Escherichia coli li...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Jin, Xin, Uttamapinant, Chayasith, Ting, Alice Y.
Бусад зохиолчид: Massachusetts Institute of Technology. Department of Chemistry
Формат: Өгүүллэг
Хэл сонгох:en_US
Хэвлэсэн: Wiley-VCH Verlag 2012
Онлайн хандалт:http://hdl.handle.net/1721.1/69559
https://orcid.org/0000-0002-8277-5226