Reinforcement-Related Regulation of AMPA Glutamate Receptor Subunits in the Ventral Tegmental Area Enhances Motivation for Cocaine

Chronic cocaine use produces numerous biological changes in brain, but relatively few are functionally associated with cocaine reinforcement. Here we show that daily intravenous cocaine self-administration, but not passive cocaine administration, induces dynamic upregulation of the AMPA glutamate re...

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Bibliographic Details
Main Authors: Choi, Kwang Ho, Edwards, Scott, Graham, Danielle L., Larson, Erin B., Whisler, Kimberly N., Simmons, Diana, Friedman, Allyson K., Walsh, Jessica J., Rahman, Zia, Monteggia, Lisa M., Eisch, Amelia J., Neve, Rachael L., Nestler, Eric J., Han, Ming-Hu, Self, David W.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Society for Neuroscience 2012
Online Access:http://hdl.handle.net/1721.1/69828
https://orcid.org/0000-0002-3854-5968