A general screening strategy for peptide-based fluorogenic ligands
A systematic and general approach for identifying efficient probes for class I PDZ domains based on environment-sensitive chromophores is presented. A series of peptides derived from the C-terminal sequence of Stargazin was first used with PDZ domains of PSD-95 and Shank3 to identify the optimal pos...
Main Authors: | , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society
2012
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Online Access: | http://hdl.handle.net/1721.1/69853 https://orcid.org/0000-0002-5749-7869 |