Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages

Dectin-1, the major β-glucan receptor in leukocytes, triggers an effective immune response upon fungal recognition. Here we use sortase-mediated transpeptidation, a technique that allows placement of a variety of probes on a polypeptide backbone, to monitor the behavior of labeled functional dectin-...

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Bibliographic Details
Main Authors: Esteban, Alexandre, Vyas, Valmik K., Strijbis, Karin, Ploegh, Hidde, Popp, Maximilian W.L., Fink, Gerald R
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2012
Online Access:http://hdl.handle.net/1721.1/69884
https://orcid.org/0000-0003-3704-2899
https://orcid.org/0000-0002-1090-6071