Rapid haplotype inference for nuclear families
Hapi is a new dynamic programming algorithm that ignores uninformative states and state transitions in order to efficiently compute minimum-recombinant and maximum likelihood haplotypes. When applied to a dataset containing 103 families, Hapi performs 3.8 and 320 times faster than state-of-the-art a...
Main Authors: | , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
BioMed Central Ltd.
2012
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Online Access: | http://hdl.handle.net/1721.1/69888 https://orcid.org/0000-0001-5016-0756 https://orcid.org/0000-0003-1709-4034 https://orcid.org/0000-0001-8095-8523 |