BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data

DNA copy number alterations (CNA), which are amplifications and deletions of certain regions in the genome, play an important role in the pathogenesis of cancer and have been shown to be associated with other diseases such as autism, schizophrenia and obesity.

Bibliographic Details
Main Authors: Xi, Ruibin, Luquette, Joe, Hadjipanayis, Angela, Kim, Tae-Min, Park, Peter J.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: BioMed Central Ltd. 2012
Online Access:http://hdl.handle.net/1721.1/69934
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author Xi, Ruibin
Luquette, Joe
Hadjipanayis, Angela
Kim, Tae-Min
Park, Peter J.
author2 Harvard University--MIT Division of Health Sciences and Technology
author_facet Harvard University--MIT Division of Health Sciences and Technology
Xi, Ruibin
Luquette, Joe
Hadjipanayis, Angela
Kim, Tae-Min
Park, Peter J.
author_sort Xi, Ruibin
collection MIT
description DNA copy number alterations (CNA), which are amplifications and deletions of certain regions in the genome, play an important role in the pathogenesis of cancer and have been shown to be associated with other diseases such as autism, schizophrenia and obesity.
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spelling mit-1721.1/699342022-09-29T19:09:03Z BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data Xi, Ruibin Luquette, Joe Hadjipanayis, Angela Kim, Tae-Min Park, Peter J. Harvard University--MIT Division of Health Sciences and Technology Park, Peter J. Park, Peter J. DNA copy number alterations (CNA), which are amplifications and deletions of certain regions in the genome, play an important role in the pathogenesis of cancer and have been shown to be associated with other diseases such as autism, schizophrenia and obesity. 2012-04-04T19:33:20Z 2012-04-04T19:33:20Z 2011-10 Article http://purl.org/eprint/type/JournalArticle 1465-6906 1474-7596 http://hdl.handle.net/1721.1/69934 Xi et al. "BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data". Genome Biology 2010 11(Suppl 1):O10. en_US http://dx.doi.org/10.1186/gb-2010-11-S1-O10 Genome Biology Creative Commons Attribution http://creativecommons.org/licenses/by/2.0 application/pdf BioMed Central Ltd. BioMed Central
spellingShingle Xi, Ruibin
Luquette, Joe
Hadjipanayis, Angela
Kim, Tae-Min
Park, Peter J.
BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data
title BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data
title_full BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data
title_fullStr BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data
title_full_unstemmed BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data
title_short BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data
title_sort bic seq a fast algorithm for detection of copy number alterations based on high throughput sequencing data
url http://hdl.handle.net/1721.1/69934
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