A high-light sensitivity optical neural silencer: development and application to optogenetic control of non-human primate cortex

Technologies for silencing the electrical activity of genetically targeted neurons in the brain are important for assessing the contribution of specific cell types and pathways toward behaviors and pathologies. Recently we found that archaerhodopsin-3 from Halorubrum sodomense (Arch), a light-driven...

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Bibliographic Details
Main Authors: Han, Xue, Chow, Brian Y., Zhou, Huihui, Klapoetke, Nathan Cao, Chuong, Amy S., Rajimehr, Reza, Yang, Aimei, Baratta, Michael V., Winkle, Jonathan Andrew, Desimone, Robert, Boyden, Edward Stuart
Other Authors: Massachusetts Institute of Technology. Synthetic Neurobiology Group
Format: Article
Language:en_US
Published: Frontiers Research Foundation 2012
Online Access:http://hdl.handle.net/1721.1/70022
https://orcid.org/0000-0002-8860-5914
https://orcid.org/0000-0003-3466-8706
https://orcid.org/0000-0002-0419-3351
https://orcid.org/0000-0002-5938-4227