High-performance genetically targetable optical neural silencing by proton pumps

The ability to silence the activity of genetically specified neurons in a temporally precise fashion would provide the opportunity to investigate the causal role of specific cell classes in neural computations, behaviours and pathologies. Here we show that members of the class of light-driven outwar...

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Bibliographic Details
Main Authors: Chow, Brian Y., Han, Xue, Dobry, Allison S., Qian, Xiaofeng, Chuong, Amy S., Li, Mingjie, Henninger, Michael Alan, Belfort, Gabriel M., Lin, Yingxi, Boyden, Edward Stuart, Monahan, Patrick Erin, III
Other Authors: Massachusetts Institute of Technology. Synthetic Neurobiology Group
Format: Article
Language:en_US
Published: Nature Publishing Group 2012
Online Access:http://hdl.handle.net/1721.1/70057
https://orcid.org/0000-0002-5680-2630
https://orcid.org/0000-0002-7002-1275
https://orcid.org/0000-0002-8860-5914
https://orcid.org/0000-0002-0419-3351