Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

Analogous to an assembly line, we employed a modular design for the high-throughput study of 1,536 structurally distinct nanoparticles with cationic cores and variable shells. This enabled elucidation of complexation, internalization, and delivery trends that could only be learned through evaluation...

Full description

Bibliographic Details
Main Authors: Whitehead, Kathryn Ann, Nuhn, Lutz, Sahay, Gaurav, Cheng, Hao, Jiang, Shan, Ma, Minglin, Lytton-Jean, Abigail K. R., Vegas, Arturo, Fenton, Patrick, Levins, Christopher G., Lee, Haeshin, Cortez, Christina, Collins, Sean P., Li, Ying Fei, Jang, Janice, Querbes, William, Zurenko, Christopher, Novobrantseva, Tatiana I., Love, Kevin T, Langer, Robert S, Anderson, Daniel Griffith, Siegwart, Daniel J.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2012
Online Access:http://hdl.handle.net/1721.1/70069
https://orcid.org/0000-0002-2100-1171
https://orcid.org/0000-0002-0100-7824
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0002-3483-5132
https://orcid.org/0000-0001-9522-8208
https://orcid.org/0000-0003-4255-0492

Internet

http://hdl.handle.net/1721.1/70069
https://orcid.org/0000-0002-2100-1171
https://orcid.org/0000-0002-0100-7824
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0002-3483-5132
https://orcid.org/0000-0001-9522-8208
https://orcid.org/0000-0003-4255-0492

Similar Items