Aneuploidy: Cancer's Fatal Flaw?

Aneuploidy is a characteristic of cancer, with greater than 90% of all solid tumors in humans carrying an aberrant karyotype. Yet, whether or how this condition contributes to tumorigenesis is not understood. Here we summarize our recent findings on the effects of aneuploidy on cell physiology and p...

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Bibliographic Details
Main Authors: Williams, Bret R., Amon, Angelika B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association for Cancer Research 2012
Online Access:http://hdl.handle.net/1721.1/70082
https://orcid.org/0000-0001-9837-0314